![]() In response to the use of antifungal preparations, population of Malassezia reduces, but the bacterial population is seldom affected. Interestingly, the specific relationship between a species of Malassezia appears to be the strategy for treating dandruff. It has been debated that the quantitative microbial assessment of all kinds does not indicate the role of yeast the abundance that might have been proportional to the volume of scales which it colonizes or be responsible for the altered desquamation. ![]() During dandruff, the levels of Malassezia increase by 1.5 to 2 times its normal level. The scalp form as biocenose for various organisms such as Staphylococci spp., Propionibacterium spp., and Malassezia spp., The density of these organisms varies from 10 3 to 10 5 organisms per mm 2. Eichstedt was the first to recognize the presence of this fungus in the disease pityriasis versicolor. The role of lipophilic yeast belonging to the genus Malassezia was widely accepted to play a role in dandruff way back in 1846. There could be several etiopathologic pathways with complex mechanisms, which may cause dandruff. On the contrary, seborrhoeic dermatitis is obviously more inflammatory in nature extending outside the limit of the scalp surface. The response to treatment is commonly swift, but transient. Hence it is believed that physiological scaling process requires more of cosmetic management. Histological examination reveals the scattered presence of lymphoid cells and squirting capillaries in the papillary dermis with hints of spongiosis and focal parakeratosis.Ĭonceptually, dandruff is a dander and represents nothing more than physiologic scaling. However, many reports suggest a clear link between the two clinical entities - the mildest form of the clinical presentation of seborrhoeic dermatitis as dandruff, where the inflammation is minimal and remain subclinical. The inflammation and extension of scaling outside the scalp exclude the diagnosis of dandruff from seborrhoeic dermatitis. The spectrum of dandruff is difficult to define because it blurs with seborrhoeic dermatitis and some other scaly conditions.
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